I'd hope so. The idea of a war escalating to become the biggest armoured conflict in Imperial history... over
a dead rock has all the gloomy grotesquerie I love about the setting. Couple that with a showcase novel for the Imperial Fists and Iron Warriors, both of whom refuse to back down from their enemies;
and some foreshadowing of the Cursus of Alganar (perhaps the artefact the Iron Warriors are after?), and you've got the set up for an epic novel.
It'd also be a great place to showcase Perturabo, as 'our bitter brother' has caught my interest in the few cameos he's had; and also to show quite how deadly a virus bombing should be – my main objection to
Galaxy in Flames was that so many survived and were able to fight :s The whole point of Isstvan
used to be that it was an atrocity:
everyone – the marines, the civilisation, the planet died. I think Exterminatus gets tossed around a little too lightly in the background

*Harumph* Any way – hope that answers your question!